Publications

Epithelial Biology Lab

Selected Publications

Complete list of publications

Genetically induced mouse model for colon-specific epithelial cell tumorigenesis driven by loss of K8 and Apc

Cell Mol Gastroenterol Hepatol. 2025

Keratin Intermediate Filaments as Regulators of β-cell Structural and Functional Integrity

Sarah Baghestani

Åbo Akademi University 2025

Keratin Filaments as Regulators of Intracellular Organization and Metabolism in Colonocytes

Joel Nyström

Åbo Akademi University 2024

β-cell keratin 8 maintains islet mechanical integrity, mitochondrial ultrastructure and β-cell glucose transporter 2 plasma membrane targeting

American J Physiol Cell Physiol. 2024

Colonocyte keratins stabilize mitochondria and contribute to mitochondrial energy metabolism

American J Physiol Gastrointest Liver Physiol. 2024

The keratin-desmosome scaffold of internal epithelia in health and disease – The plot is thickening

Current Opinion in Cell Biology 2024

Defining a timeline of colon pathologies after keratin 8 loss: rapid crypt elongation and diarrhea are followed by epithelial erosion and cell exfoliation

American J Physiol Gastrointest Liver Physiol. 2024

Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [68Ga]Ga-DOTA-Siglec-9 Positron Emission Tomography in Murine Models of Inflammatory Bowel Disease

Mol Imaging Biol. 2024

Supporting microscopy learning with Ocul-AR, a virtual and augmented reality -powered mobile application

CEUR Workshop Proceedings 2023

Colonocyte keratin 7 expression is expressed de novo in inflammatory bowel diseases and associated with pathological changes and drug-resistance

Scientific Reports 2022

Keratins Couple With The Nuclear Lamina And Regulate Proliferation In Colonic Epithelial cells

Mol Biol Cell. 2022

Targeted deletion of keratin 8 in intestinal epithelial cells disrupts tissue integrity and predisposes to tumorigenesis in the colon

Cell Mol Life Sci. 2022

Keratin 7 is a constituent of the keratin network in mouse pancreatic islets and is upregulated in experimental diabetes

Int J Mol Sci. 2021

The Pancreas: Biology and Physiology

Eds John Williams and Fred Gorelick. ISBN-13: 978-1607857167; ISBN-10: 1607857162. 2021

Keratin intermediate filaments in the colon: Guardians of epithelial homeostasis

International J Biochem Cell Biol. 2020